From Washington D.C. :
(188 miles, 4-5 hours)
Take I-95 north or the Baltimore-Washington Parkway to west loop I-695 to I-83 north. Continue on I-83 north to the I-81 interchange. Follow I-81 north to Route 322/22 west. Proceed west on Route 322 to State College, and exit at the Penn State University/Innovation Park exit. Follow the??local area directions.
From Northern New Jersey:
(188 miles, 4-5 hours)
I-80 West in PA to Exit 161 (Bellefonte), Follow PA 26 South to US 220 South. Take exit 74 for Innovation Park/Penn State University. Follow the??local area directions.
From Philadelphia:
(195 miles, 4-4.5 hours):Take the Schuylkill Expressway to the PA Turnpike. Leave the Turnpike at exit 247 (Harrisburg East-formerly exit 19). Follow I-283 north to I-83. Proceed north on I-83 to the I-81 interchange. Follow I-81 south to Route 322/22 west. Proceed west on Route 322 to State College, and exit at the Penn State University/Innovation Park exit. Follow the??local area directions.
From Western Pennsylvania and Ohio:
(5 hours from the Ohio/Pennsylvania border)Take I-80 east to exit 161 (formerly exit 24). Take Route 26 south. Follow Route 26 south to US 220 South. From Route 220, take the Penn State University/Innovation Park exit. Follow the??local area directions.